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Medicine Grand Rounds - Systemic Sclerosis: Diagnosis and Management

Dr. Gordon reviews the complex pathogenesis of systemic scleroderma (SSc) and the ACR-EULAR Classification Criteria for patients who present with certain symptoms, such as skin thickening or compromised lung function. She discusses the management of early diffuse disease including what autoantibodies to order, the cancer-immune system link and the importance of blood pressure monitoring at home. She stressed the importance of the need for improved therapies; clinical trials are ongoing but often are difficult to interpret because of timing and small samples. SSc is treated with a variety of medications and stem cell transplantation, Dr. Gordon reviews the positive and negative effects of these treatment choices.

Activity Details

Start Date: September 21, 2018
End Date: September 21, 2020

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  1. Register for the learning activity by creating an account or logging in to your account.
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  4. Click Continue to navigate to the Evaluation tab; then click the Launch button to start the evaluation.
  5. Complete and Submit the evaluation and attestation form.

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  • Jessica Gordon, MD, MSc
    Hospital for Special Surgery
    Assistant Professor of Medicine
    Weill Cornell Medical College

    Jessica Gordon MD, MSc is a rheumatologist at Hospital for Special Surgery (HSS) and Assistant Professor of Medicine at Weill Cornell Medicine. She practices general rheumatology at HSS with a subspecialty focus in the care of patients with Systemic Sclerosis (SSc.) She performs clinical and translational research with a focus on the improvement of clinical outcome measures including biomarkers as well as the development of improved therapeutic modalities for patients with SSc. 

    Dr. Gordon graduated from Brown University with a BA in Biology and studied medicine at State University of New York - Stony Brook School of Medicine. She trained in Internal Medicine at Georgetown University and then at HSS – New York Presbyterian Cornell for Rheumatology fellowship. She additionally completed a Master of Science in Clinical Investigation at Cornell University.
Learning Outcome

At the conclusion of this presentation, participants will be able to describe the clinical presentation and discuss the interdisciplinary long-term management of patients with systemic sclerosis. They will be able to review the evidence-based approach to treatment considerations as well as the complexities of ongoing clinical trials.


Dartmouth-Hitchcock is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Dartmouth-Hitchcock designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Requirements for Successful Completion

In order to receive credit for this Continuing Medical Education (CME) activity, you must:

  • View the entire presentation
  • Complete the online Attestation of Attendance & Evaluation Form (you must register to access).

In accordance with the disclosure policy of Dartmouth-Hitchcock/Geisel School of Medicine at Dartmouth as well as standards set forth by the Accreditation Council on Continuing Medical Education and the Nursing Continuing Education Council standards set forth by the American Nurses Credentialing Center Commission on Accreditation, continuing medical education and nursing education activity director(s), planning committee member(s), speaker(s), author(s) or anyone in a position to control the content have been asked to disclose any financial relationship* they have to a commercial interest (any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on patients). Such disclosure is not intended to suggest or condone bias in any presentation, but is elicited to provide participants with information that might be of potential importance to their evaluation of a given activity.

The following Activity Physician Director(s), planning committee member(s), speaker(s), author(s) or anyone in a position to control the content for Systemic Sclerosis: Diagnosis and Management (Medicine Grand Rounds) have reported the following financial interest or relationship* with various companies/organizations. The Activity Director and Planning Committee member roles were resolved by altering the individual’s control over content about the products or services of the commercial interest by the Associate Dean for CME and the Department of Medicine Chair. The speaker role was resolved by validating the activity content through independent peer review by the Activity Director. All potential conflict(s) were resolved.

* Kelly Kieffer, MD ~ her spouse is a consultant for OcculoBio. 

* Richard I. Rothstein, MD ~ has research support from Baranova (research grant to Dartmouth-Hitchcock Medical Center) and has other financial interest from Takeda. 

Jessica Gordon MD, MSc ~ has research support from Immune Tolerance Network, Corbus Pharmaceuticals, Genentech via UCLA, Cumberland Pharmaceuticals, and Scleroderma Research Foundation.

Other planning committee member(s), speaker(s), activity director(s), author(s) or anyone in a position to control the content for this program report no financial interest or relationship* with any company(ies) or organizations whose product may be germane to the content of their presentations.

*A “financial interest or relationship" refers to an equity position, receipt of royalties, consultantship, funding by a research grant, receiving honoraria for educational services elsewhere, or to any other relationship to a company that provides sufficient reason for disclosure, in keeping with the spirit of the stated policy.

Provider Contact Information

Provider contact information for questions regarding accreditation of the activity:

Center for Learning and Professional Development
Dartmouth-Hitchcock Medical Center

Type:     Internet Activity (Enduring Material)
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