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Medicine Grand Rounds - Management of Familial Hypercholesterolemia and other Lipid Disorders in 2019

Dr. McGowan follows two case studies to demonstrate the management of familial hypercholesterolemia (FH); one patient who responds well to standard medication practices, and one who requires lipid apheresis and alternative lipid lowering agents. She describes the genetic character of FH, screening and diagnostic protocols that lead to clinical management and lifestyle recommendations. She emphasizes the importance of genetic screening and treatment for family members as young as two years old, as untreated hypercholesterolemia often leads to serious cardiovascular disease as early as the 4th decade of life.

Activity Details

Start Date:  September 20, 2019
End Date:  September 20, 2021

You may claim CME credit for successful completion of this online course. In order to claim credit, you must follow these steps:

  1. Register for the learning activity by creating an account or logging in to your account.
  2. Click Continue to navigate to the Activity Material tab. Click View Presentation to view the recording. View the entire presentation.
  3. Return to this Activity page.
  4. Click Continue to navigate to the Evaluation tab; then click the Launch button to start the evaluation.
  5. Complete and Submit the evaluation and attestation form.

When the evaluation is submitted, you will be awarded credit. You may access your transcript for verification of participation at any time via Your Account. Need help? Visit the Support Page, send an Email, or call the Center for Learning and Professional Development at (603) 653-1234, Option 1.

  • Mary P. McGowan, MD
    Assistant Professor of Medicine
    Section of Cardiovascular Medicine
    Geisel School of Medicine

    Mary McGowan received her medical degree from the University of Massachusetts and remained there to complete her internship and residency.  She completed her fellowship at Johns Hopkins Hospital.

    Dr. McGowan is the Co-Director of the Lipid Clinic at Dartmouth-Hitchcock Heart and Vascular Center.  She has been the principal investigator on many national and international clinical trials, and has lectured widely in the United States, Canada, Europe and Asia on cholesterol metabolism.
Learning Outcome

Participants will be able to discuss the genetics of familial hypercholesterolemia and the role of cascade screening in making the diagnosis, recognize the role of lifestyle and lipid lowering agents in the treatment of lipid disorders and describe the mechanism of action of these agents on the horizon.


Dartmouth-Hitchcock is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Dartmouth-Hitchcock designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Requirements for Successful Completion

In order to receive credit for this Continuing Medical Education (CME) activity, you must:

  • View the entire presentation
  • Complete the online Attestation of Attendance & Evaluation Form (you must register to access).

In accordance with the disclosure policy of Dartmouth-Hitchcock/Geisel School of Medicine at Dartmouth as well as standards set forth by the Accreditation Council on Continuing Medical Education and the Nursing Continuing Education Council standards set forth by the American Nurses Credentialing Center Commission on Accreditation, continuing medical education and nursing education activity director(s), planning committee member(s), speaker(s), author(s) or anyone in a position to control the content have been asked to disclose any financial relationship* they have to a commercial interest (any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on patients). Such disclosure is not intended to suggest or condone bias in any presentation, but is elicited to provide participants with information that might be of potential importance to their evaluation of a given activity.

The following Activity Physician Director(s), planning committee member(s), speaker(s), author(s) or anyone in a position to control the content for Management of Familial Hypercholesterolemia and other Lipid Disorders in 2019 (Medicine Grand Rounds) have reported the following financial interest or relationship* with various companies/organizations. The Activity Director and Planning Committee member roles were resolved by altering the individual’s control over content about the products or services of the commercial interest by the Associate Dean for CME and the Department of Medicine Chair. All potential conflict(s) were resolved.

* Kelly Kieffer, MD ~ her spouse is a consultant for OcculoBio. 

* Richard I. Rothstein, MD ~ has research support from Baranova (research grant to Dartmouth-Hitchcock Medical Center) and has other financial interest from Allurion. 

Other planning committee member(s), speaker(s), activity director(s), author(s) or anyone in a position to control the content for this program report no financial interest or relationship* with any company(ies) or organizations whose product may be germane to the content of their presentations.

*A “financial interest or relationship" refers to an equity position, receipt of royalties, consultantship, funding by a research grant, receiving honoraria for educational services elsewhere, or to any other relationship to a company that provides sufficient reason for disclosure, in keeping with the spirit of the stated policy.

Provider Contact Information

Provider contact information for questions regarding accreditation of the activity:

Center for Learning and Professional Development
Dartmouth-Hitchcock Medical Center

Type:     Internet Activity (Enduring Material)
13 Registered Users