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Medicine Grand Rounds - Gut Microbiome: Lessons from the REIMAGINE Study, Mark Pimentel, MD, FRCP(C)

Dr. Pimentel discusses small bowel and stool microbiomes, how they differ and their connection to disease. The REIMAGINE Study is archiving small bowel bacteria prevalence and type, which may lead to targeted treatments for multiple chronic conditions. Small bowel bacterial overgrowth (SIBO) appears to be a key indicator not only in gastrointestinal disorders but also in autoimmune diseases. He discusses a variety of novel treatments for common conditions based on the specific study of the small intestine microbiome.

Activity Details

Start Date:  February 28, 2020
End Date:  February 28, 2023

You may claim CME credit for successful completion of this online course. In order to claim credit, you must follow these steps:

  1. Register for the learning activity by creating an account or logging in to your account.
  2. Click Continue to navigate to the Activity Material tab. Click View Presentation to view the recording. View the entire presentation.
  3. Return to this Activity page.
  4. Click Continue to navigate to the Evaluation tab; then click the Launch button to start the evaluation.
  5. Complete and Submit the evaluation and attestation form.

When the evaluation is submitted, you will be awarded credit. You may access your transcript for verification of participation at any time via Your Account. Need help? Visit the Support Page, send an Email, or call the Center for Learning and Professional Development at (603) 653-1234, Option 1.

Learning Outcome

Participants will be able to describe the growing importance of the microbiome in human disease, contrast the small bowel and stool microbiome and discuss how the small bowel microbiome relates to human disease.

  • Mark Pimentel, MD, FRCP(C)
    Executive Director, Medically Associated Science and Technology (MAST) Program
    Professor of Medicine, Geffen School of Medicine
    Cedars-Sinai Medical Center

    About our presenter: Dr. Pimentel completed his undergraduate work in microbiology and biochemistry at the University of Manitoba, Canada. He completed his medical degree and internal medicine residency at the University of Manitoba Health Sciences Center in Winnipeg, Manitoba, Canada.

    Active in research, Dr. Pimentel has served as a principal investigator or co-investigator for numerous basic-science, translational and clinical studies in such areas as IBS, and the relationship between gut flora composition and human disease.

Dartmouth-Hitchcock is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Dartmouth-Hitchcock designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Requirements for Successful Completion

In order to receive credit for this Continuing Medical Education (CME) activity, you must:

  • View the entire presentation
  • Complete the online Attestation of Attendance & Evaluation Form (you must register to access).

In accordance with the disclosure policy of Dartmouth-Hitchcock/Geisel School of Medicine at Dartmouth as well as standards set forth by the Accreditation Council on Continuing Medical Education and the Nursing Continuing Education Council standards set forth by the American Nurses Credentialing Center Commission on Accreditation, continuing medical education and nursing education activity director(s), planning committee member(s), speaker(s), author(s) or anyone in a position to control the content have been asked to disclose any financial relationship* they have to a commercial interest (any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on patients). Such disclosure is not intended to suggest or condone bias in any presentation, but is elicited to provide participants with information that might be of potential importance to their evaluation of a given activity.

The following Activity Physician Director(s), planning committee member(s), speaker(s), author(s) or anyone in a position to control the content for Gut Microbiome: Lessons from the REIMAGINE Study (Medicine Grand Rounds) have reported the following financial interest or relationship* with various companies/organizations. The Activity Director and Planning Committee member roles were resolved by altering the individual’s control over content about the products or services of the commercial interest by the Associate Dean for CME and the Department of Medicine Chair. The speaker conflict was resolved by validating the activity content through independent peer review by Kelly Kieffer, MD. All potential conflict(s) were resolved.

* Kelly Kieffer, MD ~ her spouse is a consultant for OcculoBio. 

* Richard I. Rothstein, MD ~ has research support from Baranova (research grant to Dartmouth-Hitchcock Medical Center) and is on the Scientific Advisory Board for Allurion.

*  Mark Pimentel, MD, FRCP(C) ~ has grant/research support from National Philanthropic Trust; is a consultant for Valeant, Commonwealth, NAIA, Synthetic Biologics; is a major stockholder of Synthetic Biologics, NAIA, Gemelli Biotech; is on the speaker bureau for Valeant; has other financial interest with Cedars Sinai.

Other planning committee member(s), speaker(s), activity director(s), author(s) or anyone in a position to control the content for this program report no financial interest or relationship* with any company(ies) or organizations whose product may be germane to the content of their presentations.

*A “financial interest or relationship" refers to an equity position, receipt of royalties, consultantship, funding by a research grant, receiving honoraria for educational services elsewhere, or to any other relationship to a company that provides sufficient reason for disclosure, in keeping with the spirit of the stated policy.

Provider Contact Information

Provider contact information for questions regarding accreditation of the activity:

Center for Learning and Professional Development
Dartmouth-Hitchcock Medical Center

Type:     Internet Activity (Enduring Material)
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